Rhizobium radiobacter – a new pathogen of healthcare-associated infections
DOI:
https://doi.org/10.31073/onehealthjournal2025-IV-01Keywords:
healthcare-associated infections, Rhizobium radiobacter infection control, antibiotics, antibiotic resistanceAbstract
This paper presents the results of a study of cases of catheter-related bloodstream infections in patients with a central venous access catheter installed for long-term infusion of medications to treat the main disease. It is known that intravascular devices are a risk factor for the development of catheter-related bloodstream infections (CRBSI). Therefore, conducting an epidemiological study of implanted vascular catheters is an important component of infection control in healthcare facilities. During the bacteriological study of blood samples from the central catheter (using BACT/ALERT FA Plus, the BACT/ALERT 3D blood culture system and nutrient media), 19 cultures were obtained, which were identified as Rhizobium radiobacter using the automated VITEK-2 Systems (bioMerieux, Inc). In the vast majority, all isolated strains demonstrated high sensitivity to antibiotics. However, 100% resistance was found to some antibiotics. Isolation of Rhizobium radiobacter from the blood of patients encourages the expansion of the etiological structure of catheter-associated bloodstream infections and confirms the importance of epidemiological surveillance of implanted intravascular devices.
References
Roychoudhury A.K., Maheshwari U., Bansal N., Padhye A. (2024) Nosocomial infections in patients admitted in medical intensive care units in a tertiary health center in Western part of India and their hematological correlation. Journal of Dr. YSR University of Health Sciences 13(1):32-35. https://10.4103/jdrysruhs.jdrysruhs_153_22.
European Centre for Disease Prevention and Control (2019) Healthcare-associated infections in intensive care units. Annual Epidemiological Report for 2017. https://www.ecdc.europa.eu/sites/default/files/documents/AER_for_2017-HAI.pdf. Accessed 5 Jan 2020.
Public Health Center of MoH of Ukraine (2021) Vyznachennia odnomomentnoi rozpovsiudzhenosti infektsiinykh khvorob, poviazanykh z nadanniam medychnoi dopomohy, ta vykorystannia antymikrobnykh preparativ v zakladakh okhorony zdorovia, shcho nadaiut tsilodobovu statsionarnu dopomohu v Ukraini v 2021 rotsi. Available from: https://www.phc.org.ua/naukova-diyalnist/doslidzhennya/inshi-doslidzhennya/viznachennya-odnomomentnoi-rozpovsyudzhenosti-infekciynikh-khvorob-povyazanikh-z-nadannyam-medichnoi-dopomogi-ta-vikoristannya-antimikrobnikh-preparativ-v-zoz (in Ukrainian).
WHO (2024) WHO Country office in Ukraine annual report 2024. Available from: http:// https://www.who.int/ukraine/publications/i/item/WHO-EURO-2025-11954-51726-79169.
MoH of Ukraine (2021) Nakaz Ministerstva okhorony zdorovia Ukrainy 03.08.2021 № 1614 Pro orhanizatsiiu profilaktyky infektsii ta infektsiinoho kontroliu v zakladakh okhorony zdorovia ta ustanovakh/ zakladakh nadannia sotsialnykh posluh/ sotsialnoho zakhystu naselennia. Available from: https://zakon.rada.gov.ua/laws/show/z1318-21#Text (in Ukrainian).
European Committee on Antimicrobial Susceptibility Testing. European antimicrobial breakpoints. Basel: EUCAST, 2025. Available from: https://eucast.org/clinical_breakpoints/.
Small M., Gabe S. (2015) Intraluminal and extraluminal catheter hub contamination in patients with long-term central venous catheters receiving home parenteral nutrition. Clinical Nutrition ESPEN 10(5):200 https://doi.org/10.1016/j.clnesp.2015.03.055.
The Joint Commission. (2013) Types of central venous catheters and risk factors for pathogenesis of CLABSIs. Retrieved from https://www.jointcommission.org/resources/patient-safety-topics/infectionprevention-and-control/central-line-associated-bloodstream-infections-toolkit-andmonograph/clabsi-toolkit—chapter-1. Accessed December 29, 2017.
Balasoiu A.T., Zlatian O.M., Ghenea A.E., Davidescu L., Lungu A., Golli A.L., Udristoiu A.L., Balasoiu M. (2022). A Rare Case of Endophthalmitis with Rhizobium radiobacter, soon after a Resolved Keratitis: Case Report. Antibiotics (Basel, Switzerland), 11(7), 905. https://doi.org/10.3390/antibiotics11070905.
Aujoulat F., Marchandin H., Zorgniotti I., Masnou A., Jumas-Bilak E. (2015). Rhizobium pusense is the main human pathogen in the genus Agrobacterium/Rhizobium. Clinical microbiology and infection: the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 21(5), 472.e1–472.e4725. https://doi.org/10.1016/j.cmi.2014.12.005.
Plotkin G.R. (1980) Agrobacterium radiobacter prosthetic valve endocarditis. Ann Intern Med 93:839–40.
Tiwari S., Beriha S. (2015) Primary Bacteremia Caused by Rhizobium radiobacter in Neonate: A Rare Case Report. Journal of clinical and diagnostic research 9(10):01–2. https://doi.org/10.7860/JCDR/2015/15101.6598.
Fatma I., Selen H.K., Umit K., Saliha K.Y. (2024) Rhizobium radiobacter infection in a preterm infant and review of the literature. Jour umraniye pediatr 4(1):47–52 https://doi: 10.14744/upd.2024.28247.
Sood S., Nerurkar V., Malvankar S. (2010) Catheter associated bloodstream infection caused by R. radiobacter. Indian J Med Microbiol. 228(1):62-4. https://doi: 10.4103/0255-0857.58734.
Lai C.C., Teng L.J., Hsueh P.R., Yuan A., Tsai K.C., Tang J.L., Tien, H. F. (2004). Clinical and microbiological characteristics of Rhizobium radiobacter infections. Clinical infectious diseases: an official publication of the Infectious Diseases Society of America, 38(1), 149–153. https://doi.org/10.1086/380463.
Wang D. L., Zhao L. D., Li L. J., Zhou M. J. (2019). Septic shock caused by Rhizobium radiobacter in an elderly woman: A case report. Medicine, 98(49), e18267. https://doi.org/10.1097/MD.0000000000018267.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 One Health Journal
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
