EFFECTIVENESS COMPARISON OF TREATMENT OF FELINE ASSOCIATED BORDETELLA BRONCHISEPTICA INFECTION WITH THE IMMUNOSTIMULANTS

Ya.V. Hlushchenko; A.M. Hontar; R.V. Severyn; S.I. Symonenko; H.M. Shtager

doi:10.31073/onehealthjournal2024-IV-02

Authors

Ya.V. Hlushchenko State University of Biotechnology, Kharkiv, Ukraine https://orcid.org/0009-0000-7483-9464
A.M. Hontar State University of Biotechnology, Kharkiv, Ukraine https://orcid.org/0000-0001-7148-5226
R.V. Severyn State University of Biotechnology, Kharkiv, Ukraine https://orcid.org/0000-0003-2217-8582
S.I. Symonenko State University of Biotechnology, Kharkiv, Ukraine https://orcid.org/0000-0002-7046-2943
H.M. Shtager State University of Biotechnology, Kharkiv, Ukraine https://orcid.org/0000-0002-7632-4963

DOI:

https://doi.org/10.31073/onehealthjournal2024-IV-02

Keywords:

cats, infectious respiratory diseases, immunostimulants, immune correction, treatment

Abstract

There is a significant spread of infectious respiratory diseases among pets, which often lead to their death. Herpesviruses and caliciviruses are the main viral pathogens that cause respiratory pathology in cats, they are of etiological importance, as they have an expressed tropism for the mucous membranes of the respiratory tract. These viral pathogens can cause both mono infections and mixed or associative infections, which may include Chlamydia, Mycoplasma, and Bordetella. Infections associated with the Bordetella virus are accompanied by the development of catarrhal inflammation of the mucous membranes of the upper respiratory tract, oral cavity, and conjunctiva. The problem of treating Bordetella virus-associated infections in cats remains an urgent issue. The study of the elaboration of diagnostic kits, ways of treatment, and specific prevention of infectious diseases in cats is of paramount importance. Drugs that inhibit pathogenic microorganisms are available on the veterinary market, but direct support of the immune response is of particular importance in the treatment of associated viral respiratory infections. Such drugs exert a suppressive effect on the humoral and cellular immune response and have a strong immunomodulatory and interferon effect. As an interferon inducer, they block the transfer of viral proteins, thereby activating the body's immune response. Thus, the study of the peculiarities of the spread of feline-associated respiratory infections, as well as the improvement of their treatment plans, is an urgent issue and is important for solving the problem of this pathology.

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EFFECTIVENESS COMPARISON OF TREATMENT OF FELINE ASSOCIATED BORDETELLA BRONCHISEPTICA INFECTION WITH THE IMMUNOSTIMULANTS

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